The Journal of Toxicological Sciences

Vol.50, No.10, 2025

Characterization of the toxicological findings from 90-day and 2-year repeated-dose toxicity studies of pesticides in rats

Yu Harakawa, Minami Shibata, Hiroaki Suzuki, Naofumi Takahashi, Atsushi Shiga, Kosuke Mizuno, Takuomi Hosaka, Ryota Shizu, Jun-ichi Takeshita and Kouichi Yoshinari

J. Toxicol. Sci., Vol.50, No.10, 523-546, 2025

Successful multimodal treatment of venlafaxine overdose-induced catecholamine-refractory shock: a case report

Tomoaki Hayakawa, Akimasa Sanagawa, Kazuki Ohashi, Kazuki Kotoge, Ryohei Matsui, Tetsuya Tamura, Jun Monma-Otaki, Yoko Furukawa-Hibi and Tomonori Hattori

J. Toxicol. Sci., Vol.50, No.10, 547-554, 2025

Spermidine alleviates sepsis-induced acute kidney injury by suppressing apoptosis and inflammation through modulation of TLR4-mediated signaling

Yun Shen, Qinyi Shi, Ting Dai, Yi Cai, Mengting Sheng, Ying Qiu, Ming Yang, Sanhong Hu and Bo Cheng

J. Toxicol. Sci., Vol.50, No.10, 555-567, 2025

Activator protein-1 mediates blue light-induced phototoxicity in retinal pigment epithelial cells

Jae Rim Lee, Myeong Ryeo Kim and Kwang Won Jeong

J. Toxicol. Sci., Vol.50, No.10, 569-576, 2025

Dihydropyrazine activates the CAMKK2-AMPK-ULK1 signaling pathway in human hepatoma HepG2 cells

Madoka Sawai, Yuu Miyauchi, Hisao Kansui and Shinji Takechi

J. Toxicol. Sci., Vol.50, No.10, 577-582, 2025

Expression profiles of purinergic P1 and P2 receptors in cultured bovine aortic endothelial cells, bovine aortic smooth muscle cells, and human vascular endothelial EA.hy926 cells

Lihito Ikeuchi, Takato Hara, Kazuki Kitabatake, Fumiaki Uchiumi, Chika Yamamoto, Mitsutoshi Tsukimoto, Tomoya Fujie and Toshiyuki Kaji

J. Toxicol. Sci., Vol.50, No.10, 583-591, 2025

News & Announcement

1-May-2025: Vol.50, No.5 was released on the Web.
21-April-2025: From June 1, 2025, this journal will update its copyright policy and introduce an open Creative Commons license. Please note that the “Instructions for Authors” will be completely revised in line with this.
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2-July-2021: Impact factor 2020: The latest impact factor is 2.196.
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1-April-2021: Online Submission System (SciEd ver.2) has been released.
19-March-2021: Instructions for Authors page has been updated.
Copyright Permission page has been updated.
1-March-2021: Vol.46, No.3 was released on the Web.
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12-July-2019: Impact Factor 2018: The latest impact factor is 1.732.
2-July-2019: Vol.44, No.7 was released on the Web.
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3-August-2018: Vol.43, No.8 was released on the Web.
6-July-2018: Vol.43, No.7 was released on the Web.
27-June-2018: Impact Factor 2017: The latest impact factor is 1.719.
27-June-2018: Archive page is newly opened.
1-June-2018: Renewed HP of The Journal of Toxicological Sciences.
Notice: Instructions for Authors and Article Processing Charge are revised.

SciEd ver.1 is shown for reference only.
This journal is supported by
JSPS KAKENHI Grant Number JP19HP2004.

Title: The Journal of Toxicological Sciences

Abbreviation: J. Toxicol. Sci.

Publisher: The Japanese Society of Toxicology

Editor-in-Chief: Toshiyuki Kaji

Frequency of Publication: monthly

Editorial Office:
Faculty of Pharmaceutical Sciences
Tokyo University of Science
2641 Yamazaki, Noda 278-8510 JAPAN

E-mail: jts-ed@jtoxsci.org

ISSN	Online ISSN: 1880-3989
	Print ISSN: 0388-1350