Top 10 papers by download from our web site

January 2012

1．125 times
Heavy oil fraction induces the dysplastic sperm in male mouse
Sogo Nishimoto, Koichi Akiyama, Yoshimi Kakinuma, Shin-ichi Kitamura and Takuya Sugahara
J. Toxicol. Sci., 36: 487-491 (2011).

2．63 times
Influence of systemic administration of atelocollagen on mouse livers: an ideal biomaterial for systemic drug delivery
Shingo Ogawa, Jun Onodera, Rika Honda and Ichiro Fujimoto
J. Toxicol. Sci., 36: 751-762 (2011).

3．56 times
The influence of Parachlorella beyerinckii CK-5 on the absorption and excretion of methylmercury (MeHg) in mice
Takuya Uchikawa, Akira Yasutake, Yoshimitsu Kumamoto, Isao Maruyama, Shoichiro Kumamoto and Yotaro Ando
J. Toxicol. Sci., 35: 101-105 (2010).

4．55 times
Inhibitory effects of clinical reagents having anti-oxidative activity on transforming growth factor-β1-induced expression of α-smooth muscle actin in human fetal lung fibroblasts
Yasuo Matsuzawa, Tatsuo Kawashima, Risa Yamazaki, Erika Yamaura, Tomohiko Makiyama, Hiromichi Fujino and Toshihiko Murayama
J. Toxicol. Sci., 36: 733-740 (2011).

5．49 times
QUANTITATIVE MEASUREMENT OF SPLICED XBP1 mRNA AS AN INDICATOR OF ENDOPLASMIC RETICULUM STRESS
Morihiko HIROTA, Masato KITAGAKI, Hiroshi ITAGAKI and Setsuya AIBA
J. Toxicol. Sci., 31: 149-156 (2006).

5．49 times
Essentials for starting a pediatric clinical study (1): Pharmacokinetics in children
Tsuyoshi Yokoi
J. Toxicol. Sci., 34: SP307-SP312 (2009).

7．48 times
A novel animal model of pruritus induced by successive application of glucocorticoid to mouse skin
Katsunori Yamaura, Ryosuke Doi, Eriko Suwa and Koichi Ueno
J. Toxicol. Sci., 36: 395-401 (2011).

8．45 times
ADVANTAGES OF IN VITRO CYTOTOXICITY TESTING BY USING PRIMARY RAT HEPATOCYTES IN COMPARISON WITH ESTABLISHED CELL LINES
Kun WANG, Hidetoshi SHINDOH, Tomoaki INOUE and Ikuo HORII
J. Toxicol. Sci., 27: 229-237 (2002).

8．45 times
Cerivastatin induces type-I fiber-, not type-II fiber-, predominant muscular toxicity in the young male F344 rats
Hisakuni Obayashi, Yoshikazu Nezu, Hatsue Yokota, Naoki Kiyosawa, Kazuhiko Mori, Naoyuki Maeda, Yoshiro Tani, Sunao Manabe and Atsushi Sanbuissho
J. Toxicol. Sci., 36: 445-452 (2011).

10．43 times
Cadmium toxicity is caused by accumulation of p53 through the down-regulation of Ube2d family genes in vitro and in vivo
Maki Tokumoto, Yasuyuki Fujiwara, Akinori Shimada, Tatsuya Hasegawa, Yoshiyuki Seko, Hisamitsu Nagase and Masahiko Satoh
J. Toxicol. Sci., 36: 191-200 (2011).

10．43 times
Hepatoprotective effects of vitamin E/selenium against malathion-induced injuries on the antioxidant status and apoptosis-related gene expression in rats
Mourad A. M. Aboul-Soud, Abdulaziz M. Al-Othman, Gaber E. El-Desoky, Zeid A. Al-Othman, Kareem Yusuf, Javed Ahmad and Abdulaziz A. Al-Khedhairy
J. Toxicol. Sci., 36: 285-296 (2011).

10．43 times
Evaluation of testicular toxicology of doxorubicin based on microarray analysis of testicular specific gene expression
Hikari Takahashi, Hitoshi Tainaka, Masakazu Umezawa, Ken Takeda, Hiromitsu Tanaka, Yoshitake Nishimune and Shigeru Oshio
J. Toxicol. Sci., 36: 559-567 (2011).

10．43 times
Removal efficiency of water purifier and adsorbent for iodine, cesium, strontium, barium and zirconium in drinking water
Itaru Sato, Hiroaki Kudo and Shuji Tsuda
J. Toxicol. Sci., 36: 829-834 (2011).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology