The Journal of Toxicological Sciences

Top 10 papers by download from our web site


December 2012

1.136 times
Acute oral toxicity evaluation of symmetrically branched glycerol trimer in ddY mice
Licht Miyamoto, Masashi Watanabe, Yosuke Tomida, Mai Kono, Shoko Fujii, Tsuyoshi Matsushita, Hatsuhiko Hattori, Keisuke Ishizawa, Hisao Nemoto, Koichiro Tsuchiya
J. Toxicol. Sci., 37: 1253-1259 (2012).

2.129 times
Aberrant activation of ubiquitin D at G2 phase and apoptosis by carcinogens that evoke cell proliferation after 28-day administration in rats
Eriko Taniai, Atsunori Yafune, Hitomi Hayashi, Megu Itahashi, Yukiko Hara-Kudo, Kazuhiko Suzuki, Kunitoshi Mitsumori, Makoto Shibutani
J. Toxicol. Sci., 37: 1093-1111 (2012).

3.97 times
Altered microRNAs expression profiling in experimental silicosis rats
Wang Faxuan, Zhang Qin, Zhou Dinglun, Zhu Tao, Ren Xiaohui, Zhao Liqiang, Lan Yajia
J. Toxicol. Sci., 37: 1207-1215 (2012).

4.93 times
Repeated application of glucocorticoids exacerbate pruritus via inhibition of prostaglandin D2 production of mast cells in a murine model of allergic contact dermatitis
Katsunori Yamaura, Ryosuke Doi, Eriko Suwa, Koichi Ueno
J. Toxicol. Sci., 37: 1127-1134 (2012).

5.76 times
Fluctuations in cell proliferation, apoptosis, and cell cycle regulation at the early stage of tumor promotion in rat two-stage carcinogenesis models
Eriko Taniai, Atsunori Yafune, Masayuki Kimura, Reiko Morita, Fumiyuki Nakane, Kazuhiko Suzuki, Kunitoshi Mitsumori, Makoto Shibutani
J. Toxicol. Sci., 37: 1113-1126 (2012).

6.74 times
Increase in covalent binding of 5-hydroxydiclofenac to hepatic tissues in rats co-treated with lipopolysaccharide and diclofenac: involvement in the onset of diclofenac-induced idiosyncratic hepatotoxicity
Tomoyuki Kishida, Tomoya Onozato, Toru Kanazawa, Satoru Tanaka, Junji Kuroda
J. Toxicol. Sci., 37: 1143-1156 (2012).

7.70 times
Behavioral and biochemical characterization of rats treated chronically with thioacetamide: proposal of an animal model for hepatic encephalopathy associated with cirrhosis
Hiroshi Kawai, Takuya Ishibashi, Naomi Kudo, Yoichi Kawashima, Atsushi Mitsumoto
J. Toxicol. Sci., 37: 1165-1175 (2012).

8.66 times
Simultaneous pharmacokinetics assessment of caffeine, warfarin, omeprazole, metoprolol, and midazolam intravenously or orally administered to Microminipigs
Masayuki Mogi, Akiko Toda, Kazuhide Iwasaki, Shogo Kusumoto, Hiromi Takehara, Makiko Shimizu, Norie Murayama, Hiroyuki Izumi, Masahiro Utoh, Hiroshi Yamazaki
J. Toxicol. Sci., 37: 1157-1164 (2012).

9.65 times
Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube
Atsuya Takagi, Akihiko Hirose, Tetsuji Nishimura, Nobutaka Fukumori, Akio Ogata, Norio Ohashi, Satoshi Kitajima, Jun Kanno
J. Toxicol. Sci., 33: 105-116 (2008).

10.63 times
Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models
Taishi Miyashita, Yasuyuki Toyoda, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima, Tsuyoshi Yokoi
J. Toxicol. Sci., 37: 931-942 (2012).


The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology