The Journal of Toxicological Sciences

Top 10 papers by download from our web site


December 2021

1. 128 times
Bisphenol A induces cholesterol biosynthesis in HepG2 cells via SREBP-2/HMGCR signaling pathway
Qingrong Li, Hongmin Zhang, Jun Zou, Xiang Feng, Dan Feng
J. Toxicol. Sci., 44: 481-491

2. 114 times
Mechanisms of CCl4-induced liver fibrosis with combined transcriptomic and proteomic analysis
Shu Dong, Qi-Long Chen, Ya-Nan Song, Yang Sun, Bin Wei, Xiao-Yan Li, Yi-Yang Hu, Ping Liu, Shi-Bing Su
J. Toxicol. Sci., 41: 561-572

3. 105 times
Understanding dabs: contamination concerns of cannabis concentrates and cannabinoid transfer during the act of dabbing
Jeffrey C. Raber, Sytze Elzinga, Charles Kaplan
J. Toxicol. Sci., 40: 797-803

4. 102 times
Effects of excessive sodium chloride loading in the spontaneously diabetic torii (SDT) fatty rats, a preclinical model of type 2 diabetes mellitus
Soon Hui Teoh, Katsuhiro Miyajima, Yuichi Shinozaki, Masami Shinohara, Keiichi Ohata, François Briand, Rika Morimoto, Yuka Nakamura, Kinuko Uno, Noriko Kemuriyama, Dai Nakae, Takeshi Ohta, Tatsuya Maekawa
J. Toxicol. Sci., 46: 589-599

5. 95 times
Association between in vitro nuclear receptor-activating profiles of chemical compounds and their in vivo hepatotoxicity in rats
Susumu Kodama, Nao Yoshii, Akihiro Ota, Jun-ichi Takeshita, Kouichi Yoshinari, Atsushi Ono
J. Toxicol. Sci., 46: 569-587

6. 92 times
Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes
Yingying Huang, Yingjun Liao, Huijun Zhang, Shuyun Li
J. Toxicol. Sci., 45: 559-567

7. 89 times
Elucidation of the species differences of epyrifenacil-induced hepatotoxicity between mice and humans by mass spectrometry imaging analysis in chimeric mice with humanized liver
Kohei Matsunaga, Jun Abe, Keiko Ogata, Satoki Fukunaga, Sachiko Kitamoto
J. Toxicol. Sci., 46: 601-609

8. 86 times
Development challenges associated with rAAV-based gene therapies
Michael W. Bolt, Joseph T. Brady, Lawrence O. Whiteley, K. Nasir Khan
J. Toxicol. Sci., 46: 57-68

9. 83 times
Detection of double-stranded DNA breaks and apoptosis induced by bleomycin in mouse intestine
Togo Ikuta, Aki Koike, Manabu Koike
J. Toxicol. Sci., 46: 611-618

10. 81 times
Pharmacokinetics of primary metabolites 5-hydroxythalidomide and 5′-hydroxythalidomide formed after oral administration of thalidomide in the rabbit, a thalidomide-sensitive species
Makiko Kuwagata, Takuro Hasegawa, Hiromasa Takashima, Makiko Shimizu, Satoshi Kitajima, Hiroshi Yamazaki
J. Toxicol. Sci., 46: 553-560


The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology