The Journal of Toxicological Sciences

Top 10 papers by download from our web site


July 2022

1. 199 times
Assessment of metabolic activation of felbamate in chimeric mice with humanized liver in combination with in vitro metabolic assays
Koya Sato, Seigo Sanoh, Yuji Ishida, Chise Tateno, Shigeru Ohta, Yaichiro Kotake
J. Toxicol. Sci., 47: 277-288

2. 187 times
Effects of microsampling on toxicity assessment of hematotoxic compounds in a general toxicity study in rats
Tomoaki Tochitani, Yasuhiro Sasaki, Naoe Nishimura, Yuta Fujii, Takayuki Iwaisako, Naohisa Umeya, Masayo Hashimoto, Hiroshi Inada, Kazuhiro Chihara, Izuru Miyawaki
J. Toxicol. Sci., 47: 269-276

3. 168 times
Inhibition of autophagy with expression of NADPH oxidase subunit p22phox in preneoplastic lesions in a high-fat diet and streptozotocin-related hepatocarcinogenesis rat model
Ryo Ichikawa, Sosuke Masuda, Junta Nakahara, Mio Kobayashi, Risako Yamashita, Suzuka Uomoto, Ohshima Kanami, Erika Hara, Yuko Ito, Makoto Shibutani, Toshinori Yoshida
J. Toxicol. Sci., 47: 289-300

4. 159 times
Estradiol dominance induces hemodilution and mild hematological alterations in mifepristone-treated rats
Ikuro Takakura, Tomoyuki Kishida, Ryohei Yokoi, Shinji Souma
J. Toxicol. Sci., 47: 301-308

5. 113 times
Mechanisms of CCl4-induced liver fibrosis with combined transcriptomic and proteomic analysis
Shu Dong, Qi-Long Chen, Ya-Nan Song, Yang Sun, Bin Wei, Xiao-Yan Li, Yi-Yang Hu, Ping Liu, Shi-Bing Su
J. Toxicol. Sci., 41: 561-572

6. 100 times
Understanding dabs: contamination concerns of cannabis concentrates and cannabinoid transfer during the act of dabbing
Jeffrey C. Raber, Sytze Elzinga, Charles Kaplan
J. Toxicol. Sci., 40: 797-803

7. 94 times
Microphysiological systems in early stage drug development: Perspectives on current applications and future impact
Anna K. Kopec, Ryuji Yokokawa, Nasir Khan, Ikuo Horii, James E. Finley, Christine P. Bono, Carol Donovan, Jessica Roy, Julie Harney, Andrew D. Burdick, Bart Jessen, Shuyan Lu, Mark Collinge, Ramin Banan Sadeghian, Mazin Derzi, Lindsay Tomlinson, John E. Burkhardt
J. Toxicol. Sci., 46: 99-114

8. 74 times
Development challenges associated with rAAV-based gene therapies
Michael W. Bolt, Joseph T. Brady, Lawrence O. Whiteley, K. Nasir Khan
J. Toxicol. Sci., 46: 57-68

9. 67 times
Macrophage differentiation induced by PMA is mediated by activation of RhoA/ROCK signaling
Lifeng Yang, Fan Dai, Lian Tang, Yulan Le, Wenjuan Yao
J. Toxicol. Sci., 42: 763-771

10. 61 times
Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet
Shiro Watanabe, Koichi Tsuneyama
J. Toxicol. Sci., 38: 379-390


The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology