Top 10 papers by download from our web site

July 2008

1．432 times
Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube
Atsuya Takagi, Akihiko Hirose, Tetsuji Nishimura, Nobutaka Fukumori, Akio Ogata, Norio Ohashi, Satoshi Kitajima and Jun Kanno
J. Toxicol. Sci., 33:105-116(2008).

2．154 times
COMMON PATHOGENIC MECHANISM IN DEVELOPMENT PROGRESSION OF LIVER INJURY CAUSED BY NON-ALCOHOLIC OR ALCOHOLIC STEATOHEPATITIS
Kiyoshi NAGATA, Hiroyuki SUZUKI and Shuhei SAKAGUCHI
J. Toxicol. Sci., 32:453-468(2007).

3．117 times
Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients
Katsumi Fukino, Yuka Sasaki, Shigekazu Hirai, Takayuki Nakamura, Masayo Hashimoto, Fumio Yamagishi and Koichi Ueno
J. Toxicol. Sci., 33:187-195(2008).

4．102 times
Points to consider on the non-clinical safety evaluation of anticancer drugs
Dai Nakae, Horoshi Onodera, Osamu Fueki, Tsutomu Urano, Noriyuki Komiyama, Fumio Sagami, Shuichi Kai, Chihiro Nishimura and Tohru Inoue
J. Toxicol. Sci., 33:123-126(2008).

5．78 times
Concurrent administration of ascorbic acid enhances liver tumor-promoting activity of kojic acid in rats
Masayoshi Takabatake, Makoto Shibutani, Yasuaki Dewa, Jihei Nishimura, Hironobu Yasuno, Meilan Jin, Masako Muguruma, Taichi Kono and Kunitoshi Mitsumori
J. Toxicol. Sci., 33:127-140(2008).

6．77 times
Gene expression profiling of methapyrilene-induced hepatotoxicity in rat
Takeki Uehara, Naoki Kiyosawa, Mitsuhiro Hirode, Ko Omura, Toshinobu Shimizu, Atsushi Ono, Yumiko Mizukawa, Toshikazu Miyagishima, Taku Nagao and Tetsuro Urushidani
J. Toxicol. Sci., 33:37-50(2008).

7．72 times
An aminoglycoside antibiotic gentamycin induces oxidative stress, reduces antioxidant reserve and impairs spermatogenesis in rats
Kilarkaje Narayana
J. Toxicol. Sci., 33:85-96(2008).

8．61 times
PROFILING OF GENE EXPRESSION IN RAT LIVER AND RAT PRIMARY CULTURED HEPATOCYTES TREATED WITH PEROXISOME PROLIFERATORS
Kotaro TAMURA, Atsushi ONO, Toshikazu MIYAGISHIMA, Taku NAGAO and Tetsuro URUSHIDANI
J. Toxicol. Sci., 31:471-490(2006).

8．61 times
Production of IL-8 in THP-1 cells following contact allergen stimulation via mitogen-activated protein kinase activation or tumor necrosis factor-α production
Yuko Nukada, Masaaki Miyazawa, Nanae Kosaka, Yuichi Ito, Hitoshi Sakaguchi and Naohiro Nishiyama
J. Toxicol. Sci., 33:175-185(2008).

10．52 times
CHANGES OF MICRO-RNA EXPRESSION IN RAT LIVER TREATED BY ACETAMINOPHEN OR CARBON TETRACHLORIDE − REGULATING ROLE OF MICRO-RNA FOR RNA EXPRESSION −
Tamio FUKUSHIMA, Yoshimasa HAMADA, Hiroshi YAMADA and Ikuo HORII
J. Toxicol. Sci., 32:401-409(2007).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology