Top 10 papers by download from our web site

August 2008

1．300 times
Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube
Atsuya Takagi, Akihiko Hirose, Tetsuji Nishimura, Nobutaka Fukumori, Akio Ogata, Norio Ohashi, Satoshi Kitajima and Jun Kanno
J. Toxicol. Sci., 33:105-116(2008).

2．212 times
Risk of human health by particulate matter as a source of air pollution -Comparison with tobacco smoking-
Makoto Enomoto, William J. Tierney and Kohsuke Nozaki
J. Toxicol. Sci., 33:251-267(2008).

3．189 times
Safety assessment of biopharmaceuticals: Japanese perspective on ICH S6 guideline maintenance
Takahiro Nakazawa, Misao Kurokawa, Kazuya Kimura, Akihiro Wakata, Shigeru Hisada, Tadashi Inoue, Fumio Sagami, Shawn M. Heidel, Koji Kawakami, Kazutoshi Shinoda, Hiroshi Onodera, Yuji Kumagai, Yasuo Ohno, Nobuyuki Kawamura, Tsuneyoshi Yamazaki and Tohru Inoue
J. Toxicol. Sci., 33:277-282(2008).

4．153 times
COMMON PATHOGENIC MECHANISM IN DEVELOPMENT PROGRESSION OF LIVER INJURY CAUSED BY NON-ALCOHOLIC OR ALCOHOLIC STEATOHEPATITIS
Kiyoshi NAGATA, Hiroyuki SUZUKI and Shuhei SAKAGUCHI
J. Toxicol. Sci., 32:453-468(2007).

5．137 times
Hypothyroidism protects di(n-butyl) phthalate-induced reproductive organs damage in Sprague-Dawley male rats
Ena Lee, Hee Jin Kim, Ji Young Im, Jeonga Kim, Hyeyoung Park, Ju Young Ryu, Jaewon Lee, Keun Aee Shim, Kee Kyung Jung, Soon Young Han, Byung Mu Lee, Seung Hee Kim and Hyung Sik Kim
J. Toxicol. Sci., 33:299-306(2008).

6．92 times
Comparison of gene expression changes induced by biguanides in db/db mice liver
Masayuki Heishi, Koji Hayashi, Junji Ichihara, Hironori Ishikawa, Takao Kawamura, Masaharu Kanaoka, Mutsuo Taiji and Toru Kimura
J. Toxicol. Sci., 33:339-347(2008).

7．87 times
Endocrine disruption induced by organotin compounds; organotins function as a powerful agonist for nuclear receptors rather than an aromatase inhibitor
Tsuyoshi Nakanishi
J. Toxicol. Sci., 33:269-276(2008).

8．81 times
(-)-Epigallocatechin 3-O-gallate (EGCG) -induced apoptosis in normal rat kidney interstitial fibroblast (NRK-49F) cells
Yohei Miyamoto, Mariko Sano, John L. Haylor and A. Meguid El Nahas
J. Toxicol. Sci., 33:367-370(2008).

9．78 times
Toxicokintic and toxicodynamic analysis of clofibrate based on free drug concentrations in nagase analbuminemia rats (NAR)
Hiroaki Miida, Shingo Arakawa, Yukari Shibaya, Kumi Honda, Naoki Kiyosawa, Kyoko Watanabe, Sunao Manabe, Wataru Takasaki and Koichi Ueno
J. Toxicol. Sci., 33: 349-361(2008).

10．76 times
Pesticide resistance in wild mammals - Mechanisms of anticoagulant resistance in wild rodents -
Mayumi Ishizuka, Tsutomu Tanikawa, Kazuyuki D. Tanaka, Min Heewon, Fumie Okajima, Kentaro Q. Sakamoto and Shoichi Fujita
J. Toxicol. Sci., 33: 283-291(2008).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology