Top 10 papers by download from our web site

April 2010

1．217 times
Involvement of metallothionein (MT) as a biological protective factor against carcinogenesis induced by benzo[a]pyrene (B[a]P)
Masaki Takaishi, Akinori Shimada, Junko S. Suzuki, Masahiko Satoh and Hisamitsu Nagase
J. Toxicol. Sci., 35: 225-230 (2010).

2．181 times
Involvement of autophagy via mammalian target of rapamycin (mTOR) inhibition in tributyltin-induced neuronal cell death
Yusuke Nakatsu, Yaichiro Kotake, Naoko Takai and Shigeru Ohta
J. Toxicol. Sci., 35: 245-251 (2010).

3．165 times
Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol
Leslie Recio, Cheryl Hobbs, William Caspary and Kristine L. Witt
J. Toxicol. Sci., 35: 149-162 (2010).

4．153 times
PHENYTOIN STIMULATES CHONDROGENIC DIFFERENTIATION IN MOUSE CLONAL CHONDROGENIC EC CELLS, ATDC5
Akinobu OKADA, Teruaki SHIOMI, Yoshinobu AOKI and Michio FUJIWARA
J. Toxicol. Sci., 30: 145-156 (2005).

5．143 times
Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-α) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes
Adarsh Gandhi, Tao Guo and Romi Ghose
J. Toxicol. Sci., 35: 163-173 (2010).

6．117 times
Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube
Atsuya Takagi, Akihiko Hirose, Tetsuji Nishimura, Nobutaka Fukumori, Akio Ogata, Norio Ohashi, Satoshi Kitajima and Jun Kanno
J. Toxicol. Sci., 33: 105-116 (2008).

7．109 times
COMMON PATHOGENIC MECHANISM IN DEVELOPMENT PROGRESSION OF LIVER INJURY CAUSED BY NON-ALCOHOLIC OR ALCOHOLIC STEATOHEPATITIS
Kiyoshi NAGATA, Hiroyuki SUZUKI and Shuhei SAKAGUCHI
J. Toxicol. Sci., 32: 453-468 (2007).

8．85 times
Study on penetration of titanium dioxide (TiO₂) nanoparticles into intact and damaged skin in vitro
Mika Senzui, Toshiaki Tamura, Keiko Miura, Yoshiaki Ikarashi, Yoshiteru Watanabe and Makiko Fujii
J. Toxicol. Sci., 35: 107-113 (2010).

9．78 times
Intrauterine environment-genome interaction and Children’s development (1): Ethanol: a teratogen in developing brain
Yoshihiro Fukui and Hiromi Sakata-Haga
J. Toxicol. Sci., 34: SP273-SP278 (2009).

10．77 times
Extracellular signal-regulated kinase (ERK) inhibition attenuates cigarette smoke extract (CSE) induced-death inducing signaling complex (DISC) formation in human lung fibroblasts (MRC-5) cells
Jeong-Woong Park, Jin Young Yoon, Yu Jin Kim, Sun Young Kyung, Sang Pyo Lee, Sung Hwan Jeong and Chanil Moon
J. Toxicol. Sci., 35: 33-39 (2010).

10．77 times
Neuroprotective effect of Centella asiatica extract (CAE) on experimentally induced parkinsonism in aged Sprague-Dawley rats
Nagaraja Haleagrahara and Kumar Ponnusamy
J. Toxicol. Sci., 35: 41-47 (2010).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology