Top 10 papers by download from our web site

October 2012

1．147 times
Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models
Taishi Miyashita, Yasuyuki Toyoda, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima, Tsuyoshi Yokoi
J. Toxicol. Sci., 37: 931-942 (2012).

2．142 times
Impact of cigarette smoke exposure on the expression of cardiac hypertrophic genes, cytochrome P450 enzymes, and oxidative stress markers in rats
Mohamed N. Al-Arifi, Zaid H. Maayah, Ali A. AlShamrani, Hesham M. Korashy
J. Toxicol. Sci., 37: 1083-1090 (2012).

3．115 times
Nephrotoxic effect of subchronic exposure to S-(1,2-dichlorovinyl)-L-cysteine in mice
Nobuaki Shirai, Mareki Ohtsuji, Keitaro Hagiwara, Hiroki Tomisawa, Naomi Ohtsuji, Sachiko Hirose, Hiromi Hagiwara
J. Toxicol. Sci., 37: 871-878 (2012).

4．96 times
Ovariectomized mouse uterotrophic assay of 36 chemicals
Ryo Ohta, Atsuya Takagi, Hideo Ohmukai, Hideki Marumo, Atsushi Ono, Yuko Matsushima, Tohru Inoue, Hiroshi Ono, Jun Kanno
J. Toxicol. Sci., 37: 879-889 (2012).

5．90 times
Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients
Kazuma Kondo, Naohito Yamada, Yusuke Suzuki, Kaoru Toyoda, Tatsuji Hashimoto, Akemi Takahashi, Akio Kobayashi, Toshiyuki Shoda, Hideyuki Kuno, Shoichiro Sugai
J. Toxicol. Sci., 37: 911-929 (2012).

6．82 times
Increased production of reactive oxygen species by the vacuolar-type (H⁺)-ATPase inhibitors bafilomycin A1 and concanamycin A in RAW 264 cells
Aya Yokomakura, JangJa Hong, Kazuo Ohuchi, Seong-Eun Oh, Jin-Yong Lee, Nariyasu Mano, Tsutomu Takahashi, Gi-Wook Hwang, Akira Naganuma
J. Toxicol. Sci., 37: 1045-1048 (2012).

7．81 times
Evaluation of in vitro screening system for estrogenicity: comparison of stably transfected human estrogen receptor-α transcriptional activation (OECD TG455) assay and estrogen receptor (ER) binding assay
Hae Kyung Lee, Tae Sung Kim, Chang Yeong Kim, Il Hyun Kang, Mi Gyeong Kim, Ki Kyung Jung, Hyung Sik Kim, Soon Young Han, Hae Jung Yoon, Gyu Seek Rhee
J. Toxicol. Sci., 37: 431-437 (2012).

8．73 times
Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube
Atsuya Takagi, Akihiko Hirose, Tetsuji Nishimura, Nobutaka Fukumori, Akio Ogata, Norio Ohashi, Satoshi Kitajima, Jun Kanno
J. Toxicol. Sci., 33: 105-116 (2008).

9．69 times
Hepatic gene expression analysis of 2-aminoanthracene exposed Fisher-344 rats reveal patterns indicative of liver carcinoma and type 2 diabetes
Worlanyo E. Gato, Dale B. Hales, Jay C. Means
J. Toxicol. Sci., 37: 1001-1016 (2012).

10．60 times
Evaluation of the testicular toxicity of prenatal exposure to bisphenol A based on microarray analysis combined with MeSH annotation
Hitoshi Tainaka, Hikari Takahashi, Masakazu Umezawa, Hiromitsu Tanaka, Yoshitake Nishimune, Shigeru Oshio, Ken Takeda
J. Toxicol. Sci., 37: 539-548 (2012).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology