Top 10 papers by download from our web site

May 2012

1．80 times
Inhibitory effects of clinical reagents having anti-oxidative activity on transforming growth factor-β1-induced expression of α-smooth muscle actin in human fetal lung fibroblasts
Yasuo Matsuzawa, Tatsuo Kawashima, Risa Yamazaki, Erika Yamaura, Tomohiko Makiyama, Hiromichi Fujino, Toshihiko Murayama
J. Toxicol. Sci., 36: 733-740 (2011).

2．79 times
Spatial learning and memory deficit of low level polybrominated diphenyl ethers-47 in male adult rat is modulated by intracellular glutamate receptors
Tang Yan, Li Xiang, Jiang Xuejun, Chen Chengzhi, Qi Youbin, Yu Xuelan, Liu Yang, Peng Changyan, Chen Hui
J. Toxicol. Sci., 37: 223-233 (2012).

3．58 times
Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats
Keisuke Shimamoto, Hitomi Hayashi, Eriko Taniai, Reiko Morita, Masako Imaoka, Yuji Ishii, Kazuhiko Suzuki, Makoto Shibutani, Kunitoshi Mitsumori
J. Toxicol. Sci., 36: 775-786 (2011).

4．57 times
Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans - toxicological implications
Hidetoshi Shindoh, Kohnosuke Nakano, Takemi Yoshida, Masaki Ishigai
J. Toxicol. Sci., 36: 411-422 (2011).

5．52 times
QUANTITATIVE MEASUREMENT OF SPLICED XBP1 mRNA AS AN INDICATOR OF ENDOPLASMIC RETICULUM STRESS
Morihiko HIROTA, Masato KITAGAKI, Hiroshi ITAGAKI, Setsuya AIBA
J. Toxicol. Sci., 31: 149-156 (2006).

6．48 times
COMMON PATHOGENIC MECHANISM IN DEVELOPMENT PROGRESSION OF LIVER INJURY CAUSED BY NON-ALCOHOLIC OR ALCOHOLIC STEATOHEPATITIS
Kiyoshi NAGATA, Hiroyuki SUZUKI, Shuhei SAKAGUCHI
J. Toxicol. Sci., 32: 453-468 (2007).

7．47 times
Expression of albumin and cytochrome P450 enzymes in HepG2 cells cultured with a nanotechnology-based culture plate with microfabricated scaffold
Kazuaki Nakamura, Natsuko Kato, Kazuko Aizawa, Reiko Mizutani, Junji Yamauchi, Akito Tanoue
J. Toxicol. Sci., 36: 625-633 (2011).

8．45 times
Removal efficiency of water purifier and adsorbent for iodine, cesium, strontium, barium and zirconium in drinking water
Itaru Sato, Hiroaki Kudo, Shuji Tsuda
J. Toxicol. Sci., 36: 829-834 (2011).

9．41 times
Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube
Atsuya Takagi, Akihiko Hirose, Tetsuji Nishimura, Nobutaka Fukumori, Akio Ogata, Norio Ohashi, Satoshi Kitajima, Jun Kanno
J. Toxicol. Sci., 33: 105-116 (2008).

9．41 times
Salbutamol inhibits lipopolysaccharide-induced inflammatory responses in rat peritoneal macrophages
Satoru Tanaka, Masaru Tsutsui, Tomoyuki Kishida, Shinji Souma, Junji Kuroda, Takemi Yoshida
J. Toxicol. Sci., 35: 327-334 (2010).

9．41 times
Changes of ghrelin and leptin levels in plasma by cigarette smoke in rats
Koichi Tomoda, Kaoru Kubo, Yasue Nishii, Yoshifumi Yamamoto, Masanori Yoshikawa, Hiroshi Kimura
J. Toxicol. Sci., 37: 131-138 (2012).

10．38 times
ADVANTAGES OF IN VITRO CYTOTOXICITY TESTING BY USING PRIMARY RAT HEPATOCYTES IN COMPARISON WITH ESTABLISHED CELL LINES
Kun WANG, Hidetoshi SHINDOH, Tomoaki INOUE, Ikuo HORII
J. Toxicol. Sci., 27: 229-237 (2002).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology