Top 10 papers by download from our web site

November 2013

1．108 times
Garcinia vilersiana bark extract activates the Nrf2/HO-1 signaling pathway in RAW264.7 cells
Yasuhiro Shinkai, Ichiro Yamanaka, Ho Huynh Thuy Duong, Nguyen Thi Quynh, Yasunori Kanaho, Yoshito Kumagai
J. Toxicol. Sci., 38: 875-878 (2013).

2．105 times
Expression of VEGF-related proteins in cultured human brain microvascular endothelial cells and pericytes after exposure to methylmercury
Takashi Hirooka, Chika Yamamoto, Akira Yasutake, Komyo Eto, Toshiyuki Kaji
J. Toxicol. Sci., 38: 837-845 (2013).

3．102 times
Methylmercury induces caspase-dependent apoptosis and autophagy in human neural stem cells
Seung-Hee Chang, Hong Ju Lee, Bitna Kang, Kyeong-Nam Yu, Arash Minai-Tehrani, Somin Lee, Seung U. Kim, Myung-Haing Cho
J. Toxicol. Sci., 38: 823-831 (2013).

4．90 times
Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung
Jun Yang, Parrisa Solaimani, Hua Dong, Bruce Hammock, Oliver Hankinson
J. Toxicol. Sci., 38: 833-836 (2013).

5．83 times
Inorganic arsenic induces apoptosis through downregulation of Ube2d genes and p53 accumulation in rat proximal tubular cells
Maki Tokumoto, Jin-Yong Lee, Yasuyuki Fujiwara, Masanobu Uchiyama, Masahiko Satoh
J. Toxicol. Sci., 38: 815-820 (2013).

6．62 times
Knockdown of the gene for homeobox protein HOXB13 reduces toxicity of oxidative-stress inducers in HEK293 cells
Ryo Nakano, Tsutomu Takahashi, Akira Naganuma, Gi-Wook Hwang
J. Toxicol. Sci., 38: 821-822 (2013).

7．61 times
Dose-dependent regional brain acetylcholinesterase and acylpeptide hydrolase inhibition without cell death after chlorpyrifos administration
Diana Cardona, Caridad López-Granero, Fernando Cañadas, Jordi Llorens, Pilar Flores, Floria Pancetti, Fernando Sánchez-Santed
J. Toxicol. Sci., 38: 193-203 (2013).

8．59 times
Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube
Atsuya Takagi, Akihiko Hirose, Tetsuji Nishimura, Nobutaka Fukumori, Akio Ogata, Norio Ohashi, Satoshi Kitajima, Jun Kanno
J. Toxicol. Sci., 33: 105-116 (2008).

9．57 times
QUANTITATIVE MEASUREMENT OF SPLICED XBP1 mRNA AS AN INDICATOR OF ENDOPLASMIC RETICULUM STRESS
Morihiko HIROTA, Masato KITAGAKI, Hiroshi ITAGAKI, Setsuya AIBA
J. Toxicol. Sci., 31: 149-156 (2006).

10．55 times
Di-(2-ethylhexyl)-phthalate reduces MyoD and myogenin expression and inhibits myogenic differentiation in C2C12 cells
Shun-Sheng Chen, Hsiao-Ting Hung, Tsan-Ju Chen, Hui-Shan Hung, Dean-Chuan Wang
J. Toxicol. Sci., 38: 783-791 (2013).

10．55 times
Phthalates residues in plastic bottled waters
Iman Al-Saleh, Neptune Shinwari, Ammar Alsabbaheen
J. Toxicol. Sci., 36: 469-478 (2011).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology