Top 10 papers by download from our web site

April 2014

1．14103 times
The CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with reduced CYP3A4 protein level and function in human liver microsomes
Maho Okubo, Norie Murayama, Makiko Shimizu, Tsutomu Shimada, F. Peter Guengerich, Hiroshi Yamazaki
J. Toxicol. Sci., 38: 349-354 (2013).

2．2101 times
A MECHANISM OF THE THEARUBIGIN FRACTION OF BLACK TEA (CAMELLIA SINENSIS) EXTRACT PROTECTING AGAINST THE EFFECT OF TETANUS TOXIN
Eiki SATOH, Toshiaki ISHII, Yoshio SHIMIZU, Shin-ichi SAWAMURA, Masakazu NISHIMURA
J. Toxicol. Sci., 27: 441-447 (2002).

3．111 times
Dietary fish oil exacerbates concanavalin A induced hepatitis through promoting hepatocyte apoptosis and altering immune cell populations
Sheng Xia, Mutian Han, Xiaoping Li, Lu Cheng, Yetao Qiang, Shuiyun Wu, Miaomiao Zhang, Huaxi Xu, Xia Liu, Qixiang Shao
J. Toxicol. Sci., 39: 179-190 (2014).

4．82 times
Involvement of epithelial-mesenchymal transition in methotrexate-induced pulmonary fibrosis
Masayuki Ohbayashi, Satoshi Kubota, Aya Kawase, Noriko Kohyama, Yasuna Kobayashi, Toshinori Yamamoto
J. Toxicol. Sci., 39: 319-330 (2014).

5．74 times
Branched-chain amino acid-rich diet improves skeletal muscle wasting caused by cigarette smoke in rats
Koichi Tomoda, Kaoru Kubo, Kazuo Hino, Yasunori Kondoh, Yasue Nishii, Noriko Koyama, Yoshifumi Yamamoto, Masanori Yoshikawa, Hiroshi Kimura
J. Toxicol. Sci., 39: 331-337 (2014).

6．62 times
An improved dispersion method of multi-wall carbon nanotube for inhalation toxicity studies of experimental animals
Yuhji Taquahashi, Yukio Ogawa, Atsuya Takagi, Masaki Tsuji, Koichi Morita, Jun Kanno
J. Toxicol. Sci., 38: 619-628 (2013).

7．50 times
Adenosine A_2B receptor antagonist PSB603 suppresses tumor growth and metastasis by inhibiting induction of regulatory T cells
Wakako Kaji, Satomi Tanaka, Mitsutoshi Tsukimoto, Shuji Kojima
J. Toxicol. Sci., 39: 191-198 (2014).

8．48 times
Exposure to zinc oxide nanoparticles affects reproductive development and biodistribution in offspring rats
Eunhye Jo, Gyounbaek Seo, Jung-Taek Kwon, Mimi Lee, Byoung cheun Lee, Igchun Eom, Philje Kim, Kyunghee Choi
J. Toxicol. Sci., 38: 525-530 (2013).

9．47 times
Teratogenicity of asbestos in mice
Tomoko Fujitani, Motoki Hojo, Akiko Inomata, Akio Ogata, Akihiko Hirose, Tetsuji Nishimura, Dai Nakae
J. Toxicol. Sci., 39: 363-370 (2014).

10．46 times
Methylmercury induces caspase-dependent apoptosis and autophagy in human neural stem cells
Seung-Hee Chang, Hong Ju Lee, Bitna Kang, Kyeong-Nam Yu, Arash Minai-Tehrani, Somin Lee, Seung U. Kim, Myung-Haing Cho
J. Toxicol. Sci., 38: 823-831 (2013).

10．46 times
New recreational drug 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (alpha-PVP) activates central nervous system via dopaminergic neuron
Asuka Kaizaki, Sachiko Tanaka, Satoshi Numazawa
J. Toxicol. Sci., 39: 1-6 (2014).

10．46 times
Involvement of hemeoxygenase-1 in di(2-ethylhexyl) phthalate (DEHP)-induced apoptosis of Neuro-2a cells
Kyaw Htet Aung, Tin-Tin Win-Shwe, Moeko Kanaya, Hirohisa Takano, Shinji Tsukahara
J. Toxicol. Sci., 39: 217-229 (2014).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology