Top 10 papers by download from our web site

May 2014

1．20080 times
An RNA synthesis inhibition assay for detecting toxic substances using click chemistry
Yukiko Kametani, Shigenori Iwai, Isao Kuraoka
J. Toxicol. Sci., 39: 293-299 (2014).

2．88 times
New recreational drug 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (alpha-PVP) activates central nervous system via dopaminergic neuron
Asuka Kaizaki, Sachiko Tanaka, Satoshi Numazawa
J. Toxicol. Sci., 39: 1-6 (2014).

3．75 times
Involvement of epithelial-mesenchymal transition in methotrexate-induced pulmonary fibrosis
Masayuki Ohbayashi, Satoshi Kubota, Aya Kawase, Noriko Kohyama, Yasuna Kobayashi, Toshinori Yamamoto
J. Toxicol. Sci., 39: 319-330 (2014).

4．70 times
Effects of valproic acid on gene expression during human embryonic stem cell differentiation into neurons
Tomo Ehashi, Noriyuki Suzuki, Satoshi Ando, Kayo Sumida, Koichi Saito
J. Toxicol. Sci., 39: 383-390 (2014).

5．58 times
Dietary fish oil exacerbates concanavalin A induced hepatitis through promoting hepatocyte apoptosis and altering immune cell populations
Sheng Xia, Mutian Han, Xiaoping Li, Lu Cheng, Yetao Qiang, Shuiyun Wu, Miaomiao Zhang, Huaxi Xu, Xia Liu, Qixiang Shao
J. Toxicol. Sci., 39: 179-190 (2014).

6．57 times
A 13-week subchronic toxicity study of grape skin extract in F344 rats
Kaoru Inoue, Tomomi Morikawa, Miwa Takahashi, Midori Yoshida, Kumiko Ogawa
J. Toxicol. Sci., 38: 559-570 (2013).

7．48 times
Purinergic signaling via P2Y receptors up-mediates IL-6 production by liver macrophages/Kupffer cells
Makiko Ishimaru, Negishi Yusuke, Mitsutoshi Tsukimoto, Hitoshi Harada, Takato Takenouchi, Hiroshi Kitani, Shuji Kojima
J. Toxicol. Sci., 39: 413-423 (2014).

8．45 times
Genotoxicity and subacute toxicity studies of a new astaxanthin-containing Phaffia rhodozyma extract
Yoshiyuki Tago, Toshihide Fujii, Jutaro Wada, Masanori Kato, Min Wei, Hideki Wanibuchi, Mitsuaki Kitano
J. Toxicol. Sci., 39: 373-382 (2014).

9．43 times
Transcript profiling analysis of in vitro cultured THP-1 cells after exposure to crotonaldehyde
Bi-cheng Yang, Zhi-hua Yang, Xiu-jie Pan, Li-meng Wang, Xing-yu Liu, Mao-xiang Zhu, Jian-ping Xie
J. Toxicol. Sci., 39: 487-497 (2014).

10．39 times
Simulation of acute reference dose (ARfD) settings for pesticides in Japan
Midori Yoshida, Daisetsu Suzuki, Kiyoshi Matsumoto, Mariko Shirota, Kaoru Inoue, Miwa Takahashi, Takeshi Morita, Atsushi Ono
J. Toxicol. Sci., 38: 205-214 (2013).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology