Top 10 papers by download from our web site

September 2014

1．76 times
Down-regulation of cyclooxygenase-2 (COX-2) by cannabidiolic acid in human breast cancer cells
Shuso Takeda, Hiroyuki Okazaki, Eriko Ikeda, Satomi Abe, Yasushi Yoshioka, Kazuhito Watanabe, Hironori Aramaki
J. Toxicol. Sci., 39: 711-716 (2014).

2．60 times
Cisplatin (CDDP) triggers cell death of MCF-7 cells following disruption of intracellular calcium ([Ca²⁺]i) homeostasis
Nawaf Al-Taweel, Elizabeth Varghese, Ana-Maria Florea, Dietrich Büsselberg
J. Toxicol. Sci., 39: 765-774 (2014).

3．56 times
S-Mercuration of cellular proteins by methylmercury and its toxicological implications
Hironori Kanda, Yasuhiro Shinkai, Yoshito Kumagai
J. Toxicol. Sci., 39: 687-700 (2014).

4．55 times
QUANTITATIVE MEASUREMENT OF SPLICED XBP1 mRNA AS AN INDICATOR OF ENDOPLASMIC RETICULUM STRESS
Morihiko HIROTA, Masato KITAGAKI, Hiroshi ITAGAKI, Setsuya AIBA
J. Toxicol. Sci., 31: 149-156 (2006).

5．54 times
Effects of valproic acid on gene expression during human embryonic stem cell differentiation into neurons
Tomo Ehashi, Noriyuki Suzuki, Satoshi Ando, Kayo Sumida, Koichi Saito
J. Toxicol. Sci., 39: 383-390 (2014).

6．53 times
Grape seed proanthocyanidins inhibit H₂O₂-induced osteoblastic MC3T3-E1 cell apoptosis via ameliorating H₂O₂-induced mitochondrial dysfunction
Zhifeng Zhang, Leigang Zheng, Zhenqun Zhao, Jun Shi, Xing Wang, Jian Huang
J. Toxicol. Sci., 39: 803-813 (2014).

7．44 times
Comparative metabolome analysis of cultured fetal and adult hepatocytes in humans
Su-Ryang Kim, Takashi Kubo, Yukie Kuroda, Maki Hojyo, Takuya Matsuo, Atsuko Miyajima, Makoto Usami, Yuko Sekino, Taku Matsushita, Seiichi Ishida
J. Toxicol. Sci., 39: 717-723 (2014).

7．44 times
Detection of a novel neurotoxic metabolite of Parkinson’s disease-related neurotoxin, 1-benzyl-1,2,3,4- tetrahydroisoquinoline
Yaichiro Kotake, Yoko Sekiya, Katsuhiro Okuda, Shigeru Ohta
J. Toxicol. Sci., 39: 749-754 (2014).

9．43 times
Effects of arecoline on hepatic cytochrome P450 activity and oxidative stress
Xiao Run-mei, Wang Jun-jun, Chen Jing-ya, Sun Li-juan, Chen Yong
J. Toxicol. Sci., 39: 609-614 (2014).

9．43 times
ADVANTAGES OF IN VITRO CYTOTOXICITY TESTING BY USING PRIMARY RAT HEPATOCYTES IN COMPARISON WITH ESTABLISHED CELL LINES
Kun WANG, Hidetoshi SHINDOH, Tomoaki INOUE, Ikuo HORII
J. Toxicol. Sci., 27: P229-237 (2002).

10．41 times
Dexmedetomidine premedication attenuates concanavalin A-induced hepatitis in mice
Haibin Wang, Baoji Hu, Yun Zou, Lulong Bo, Jun Wang, Jinbao Li, Yan Luo
J. Toxicol. Sci., 39: 755-764 (2014).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology