Top 10 papers by download from our web site

June 2015

1．115 times
General considerations in ocular toxicity risk assessment from the toxicologists' viewpoints
Hiroshi Onodera, Shoji Sasaki, Seiji Otake, Masayuki Tomohiro, Kazumoto Shibuya, Mamoru Nomura
J. Toxicol. Sci., 40: 295-307 (2015).

2．92 times
New recreational drug 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (alpha-PVP) activates central nervous system via dopaminergic neuron
Asuka Kaizaki, Sachiko Tanaka, Satoshi Numazawa
J. Toxicol. Sci., 39: 1-6 (2014).

3．77 times
Development of QSAR models using artificial neural network analysis for risk assessment of repeated-dose, reproductive, and developmental toxicities of cosmetic ingredients
Tomoka Hisaki, Maki Aiba née Kaneko, Masahiko Yamaguchi, Hitoshi Sasa, Hirokazu Kouzuki
J. Toxicol. Sci., 40: 163-180 (2015).

4．71 times
Hepatotoxicants induce cytokine imbalance in response to innate immune system
Shima Goto, Jiro Deguchi, Naoki Nishio, Naruaki Nomura, Hitoshi Funabashi
J. Toxicol. Sci., 40: 389-404 (2015).

5．61 times
Thyroid and growth hormone concentrations in 8-year-old children exposed in utero to dioxins and polychlorinated biphenyls
Pen-Hua Su, Hsiao-Yen Chen, Suh-Jen Chen, Jia-Yuh Chen, Saou-Hsing Liou, Shu-Li Wang
J. Toxicol. Sci., 40: 309-319 (2015).

5．61 times
Aluminum and benzo[a]pyrene co-operate to induce neuronal apoptosis in vitro
Yin Jinzhu, Zhang Qinli, Yang Jin, Kang Pan, Huang Jianjun, Niu Qiao
J. Toxicol. Sci., 40: 365-373 (2015).

7．60 times
QUANTITATIVE MEASUREMENT OF SPLICED XBP1 mRNA AS AN INDICATOR OF ENDOPLASMIC RETICULUM STRESS
Morihiko HIROTA, Masato KITAGAKI, Hiroshi ITAGAKI, Setsuya AIBA
J. Toxicol. Sci., 31: 149-156 (2006).

8．55 times
The role of NF-κB in PARP-inhibitor-mediated sensitization and detoxification of arsenic trioxide in hepatocellular carcinoma cells
Qingying Luo, Yang Li, Yanhao Lai, Zunzhen Zhang
J. Toxicol. Sci., 40: 349-363 (2015).

9．48 times
Aromatase knockout mice reveal an impact of estrogen on drug-induced alternation of murine electrocardiography parameters
Junko Kurokawa, Tetsuo Sasano, Masami Kodama, Min Li, Yusuke Ebana, Nobuhiro Harada, Shin-ichiro Honda, Haruaki Nakaya, Tetsushi Furukawa
J. Toxicol. Sci., 40: 339-348 (2015).

9．48 times
Biological effects of inorganic phosphate: potential signal of toxicity
Seong-Ho Hong, Sung-Jin Park, Somin Lee, Sanghwa Kim, Myung-Haing Cho
J. Toxicol. Sci., 40: 55-69 (2015).

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology