Top 10 papers by download from our web site

April 2021

1. 236 times
Mechanisms of CCl₄-induced liver fibrosis with combined transcriptomic and proteomic analysis
Shu Dong, Qi-Long Chen, Ya-Nan Song, Yang Sun, Bin Wei, Xiao-Yan Li, Yi-Yang Hu, Ping Liu, Shi-Bing Su
J. Toxicol. Sci., 41: 561-572

2. 177 times
Understanding dabs: contamination concerns of cannabis concentrates and cannabinoid transfer during the act of dabbing
Jeffrey C. Raber, Sytze Elzinga, Charles Kaplan
J. Toxicol. Sci., 40: 797-803

3. 131 times
Association of CYP1A1 and CYP1B1 inhibition in in vitro assays with drug-induced liver injury
Yuki Shimizu, Takamitsu Sasaki, Eri Yonekawa, Hirokazu Yamazaki, Rui Ogura, Michiko Watanabe, Takuomi Hosaka, Ryota Shizu, Jun-ichi Takeshita, Kouichi Yoshinari
J. Toxicol. Sci., 46: 167-176

4. 122 times
Activation of PTP1B/EGFR signaling and cytotoxicity during combined exposure to ambient electrophiles in A431 cells
Yumi Abiko, Kohki Kurosawa, Hiroto Yamakawa, Yoshito Kumagai
J. Toxicol. Sci., 46: 177-185

5. 103 times
Arsenite induces tissue factor synthesis through Nrf2 activation in cultured human aortic smooth muscle cells
Tsuyoshi Nakano, Tsutomu Takahashi, Chika Yamamoto, Toshiyuki Kaji, Yasuyuki Fujiwara
J. Toxicol. Sci., 46: 187-192

6. 93 times
A 28-day repeated oral dose toxicity study of enniatin complex in mice
Hiromu Okano, Toshiya Okamura, Yasunori Takahashi, Kazumi Takashima, Ryota Ojiro, Qian Tang, Meilan Jin, Satomi Kikuchi, Bunichiro Ogawa, Toshinori Yoshida, Tomoya Yoshinari, Makoto Shibutani
J. Toxicol. Sci., 46: 157-165

7. 91 times
Cardio-renal safety of non-steroidal anti-inflammatory drugs
Zaher A. Radi, K. Nasir Khan
J. Toxicol. Sci., 44: 373-391

8. 81 times
Microphysiological systems in early stage drug development: Perspectives on current applications and future impact
Anna K. Kopec, Ryuji Yokokawa, Nasir Khan, Ikuo Horii, James E. Finley, Christine P. Bono, Carol Donovan, Jessica Roy, Julie Harney, Andrew D. Burdick, Bart Jessen, Shuyan Lu, Mark Collinge, Ramin Banan Sadeghian, Mazin Derzi, Lindsay Tomlinson, John E. Burkhardt
J. Toxicol. Sci., 46: 99-114

9. 80 times
Development challenges associated with rAAV-based gene therapies
Michael W. Bolt, Joseph T. Brady, Lawrence O. Whiteley, K. Nasir Khan
J. Toxicol. Sci., 46: 57-68

10. 79 times
Macrophage differentiation induced by PMA is mediated by activation of RhoA/ROCK signaling
Lifeng Yang, Fan Dai, Lian Tang, Yulan Le, Wenjuan Yao
J. Toxicol. Sci., 42: 763-771

The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology