14th, 2024

Title:

A rapid screening assay for L452R and T478K spike mutations in SARS-CoV-2 Delta variant using high-resolution melting analysis

Author:

Akira Aoki, Hirokazu Adachi, Yoko Mori, Miyabi Ito, Katsuhiko Sato, Kenji Okuda, Toru Sakakibara, Yoshinori Okamoto, Hideto Jinno

J. Toxicol. Sci., Vol. 46, No. 10, 471-476, 2021

Title:

Environmental cadmium exposure induces kidney tubular and glomerular dysfunction in the Myanmar adults

Author:

Muyar Win-Thu, Ohnmar Myint-Thein, Tin-Tin Win-Shwe, Ohn Mar

J. Toxicol. Sci., Vol. 46, No. 7, 319-328, 2021

Title:

Adverse effects of methylmercury on gut bacteria and accelerated accumulation of mercury in organs due to disruption of gut microbiota

Author:

Natsumi Seki, Masahiro Akiyama, Hiroto Yamakawa, Koji Hase, Yoshito Kumagai, Yun-Gi Kim

J. Toxicol. Sci., Vol. 46, No. 2, 91-97, 2021

Title:

Chronic cardiotoxicity assessment of BMS-986094, a guanosine nucleotide analogue, using human iPS cell-derived cardiomyocytes

Author:

Shota Yanagida, Ayano Satsuka, Sayo Hayashi, Atsushi Ono, Yasunari Kanda

J. Toxicol. Sci., Vol. 46, No. 8, 359-369, 2021

13th, 2023

Title:

Involvement of metal transporters in the intestinal uptake of cadmium

Author:

Hisayoshi Ohta, Kenichi Ohba

J. Toxicol. Sci. Vol.45, No.9, 539-548, 2020

Title:

A novel screening test to predict the developmental toxicity of drugs using human induced pluripotent stem cells

Author:

Nobuo Aikawa

J. Toxicol. Sci. Vol.45, No.4, 187-199, 2020

Title:

Cannabidiolic acid dampens the expression of cyclooxygenase-2 in MDA-MB-231 breast cancer cells: Possible implication of the peroxisome proliferator-activated receptor β/δ abrogation

Author:

Masayo Hirao-Suzuki, Shuso Takeda, Takayuki Koga, Masufumi Takiguchi, Akihisa Toda

J. Toxicol. Sci. Vol.45, No.4, 227-236, 2020

12th, 2022

Title:

Comparison of the developmental/reproductive toxicity and hepatotoxicity of phthalate esters in rats using an open toxicity data source

Author:

Kaori Ambe, Yuko Sakakibara, Aya Sakabe, Hayato Makino, Tatsuya Ochibe, Masahiro Tohkin

J. Toxicol. Sci. Vol.44, No.4, 245-255, 2019

Title:

Intracellular accumulation-independent cytotoxicity of pentavalent organoantimony compounds in cultured vascular endothelial cells

Author:

Takato Hara, Shihoko Nakano, Yuki Kitamura, Chika Yamamoto, Shuji Yasuike, Toshiyuki Kaji

J. Toxicol. Sci. Vol.44, No.12, 845-848, 2019

Title:

Possible mechanisms underlying transcriptional induction of metallothionein isoforms by tris(pentafluorophenyl)stibane, tris(pentafluorophenyl)arsane, and tris(pentafluorophenyl)phosphane in cultured bovine aortic endothelial cells

Author:

Tomoya Fujie, Fukuta Takenaka, Eiko Yoshida, Shuji Yasuike, Yasuyuki Fujiwara, Yasuhiro Shinkai, Yoshito Kumagai, Chika Yamamoto, Toshiyuki Kaji

J. Toxicol. Sci. Vol.44, No.5, 327-333, 2019

Title:

Segment-specific and direction-dependent transport of cadmium and manganese in immortalized S1, S2, and S3 cells derived from mouse kidney proximal tubules

Author:

Hitomi Fujishiro, Satoko Hamao, Misaki Isawa, Seiichiro Himeno

J. Toxicol. Sci. Vol.44, No.9, 611-619, 2019

11th, 2021

Title:

A long-term culture system based on a collagen vitrigel membrane chamber that supports liver-specific functions of hepatocytes isolated from mice with humanized livers

Author:

Ryuji Watari, Motoharu Kakiki, Ayumi Oshikata, Toshiaki Takezawa, Chihiro Yamasaki, Yuji Ishida, Chise Tateno, Yukie Kuroda, Seiichi Ishida, Kazutomi Kusano

J. Toxicol. Sci. Vol.43, No.8, 521-529, 2018

Title:

Comparative study for carcinogenicity of 7 different multi-wall carbon nanotubes with different physicochemical characteristics by a single intraperitoneal injection in male Fischer 344 rats

Author:

Yoshimitsu Sakamoto, Motoki Hojo, Yuki Kosugi, Kimiyo Watanabe, Akihiko Hirose, Akiko Inomata, Toshinari Suzuki, Dai Nakae

J. Toxicol. Sci. Vol.43, No.10, 587-600, 2018

Title:

Bisphenol AF as an activator of human estrogen receptor β1 (ER β1) in breast cancer cell lines

Author:

Hiroyuki Okazaki, Masayo Hirao-Suzuki, Shuso Takeda, YukimiTakemoto, Ramu Mizunoe, Koichi Haraguchi, Kazuhito Watanabe, Masufumi Takiguchi, Hironori Aramaki Hironori Aramaki

J. Toxicol. Sci. Vol.43, No.5, 321-327, 2018

Title:

Increased susceptibility to troglitazone-induced mitochondrial permeability transition in type 2 diabetes mellitus model rat

Author:

Masahiro Segawa, Shuichi Sekine, Tomoyuki Sato, Kousei Ito

J. Toxicol. Sci. Vol.43, No.5, 339-351, 2018

Title:

Photodynamic therapy using talaporfin sodium induces heme oxygenase-1 expression in rat malignant meningioma KMY-J cells

Author:

Tsutomu Takahashi, Saki Suzuki, Suzuka Misawa, Jiro Akimoto, Yo Shinoda, Yasuyuki Fujiwara

J. Toxicol. Sci. Vol.43, No.5, 353-358, 2018

Title:

Social behavior, neuroimmune markers and glutamic acid decarboxylase levels in a rat model of valproic acid-induced autism

Author:

Tin-Tin Win-Shwe, Nay Chi Nway, Motoki Imai, Thet-Thet Lwin, Ohn Mar, Hidehiro Watanabe

J. Toxicol. Sci. Vol.43, No.11, 631-643, 2018

10th, 2020

Title:

Tobacco nitrosamine NNK increases ALDH-positive cells via ROS-Wnt signaling pathway in A549 human lung cancer cells

Author:

Naoya Hirata, Shigeru Yamada, Yuko Sekino, Yasunari Kanda

J. Toxicol. Sci. Vol.42, No.2, 193-204, 2017

Title:

Characterization of human iPS cell-derived cardiomyocyte sheets as a model to detect drug-induced conduction disturbance

Author:

Hiroko Izumi-Nakaseko, Yuji Nakamura, Takeshi Wada, Kentaro Ando, Yasunari Kanda, Yuko Sekino, Atsushi Sugiyama

J. Toxicol. Sci. Vol.42, No.2, 183-192, 2017

Title:

Chronotoxicity of bromobenzene-induced hepatic injury in mice

Author:

Hiroki Yoshioka, Tsunemasa Nonogaki, Nobuyuki Fukuishi, Yasuro Shinohara, Gi-Wook Hwang, Katsumi Ohtani, Nobuhiko Miura

J. Toxicol. Sci. Vol.42, No.2, 251-258, 2017

9th, 2019

Title:

Effects of PAMAM dendrimers with various surface functional groups and multiple generations on cytotoxicity and neuronal differentiation using human neural progenitor cells

Author:

Yang Zeng, Yoshika Kurokawa, Tin-Tin Win-Shwe, Qin Zeng, Seishiro Hirano, Zhenya Zhang, Hideko Sone

J. Toxicol. Sci. Vol.41, No.3, 351-370, 2016

Title:

Carbon tetrachloride-induced lethality in mouse is prevented by multiple pretreatment with zinc sulfate

Author:

Hiroki Yoshioka, Haruki Usuda, Tsunemasa Nonogaki, Satomi Onosaka

J. Toxicol. Sci. Vol.41, No.1, 55-63, 2016

Title:

Methoxychlor and fenvalerate induce neuronal death by reducing GluR2 expression

Author:

Kanae Umeda, Yaichiro Kotake, Masatsugu Miyara, Keishi Ishida, Seigo Sanoh, Shigeru Ohta

J. Toxicol. Sci. Vol.41, No.2, 255-264, 2016

Title:

NF-κB activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol

Author:

Kei-ichi Sugiyama, Masashi Muroi, Mawo Kinoshita, Osamu Hamada, Yuji Minai, Yoshiko Sugita-Konishi, Yoichi Kamata, Ken-ichi Tanamoto

J. Toxicol. Sci. Vol.41, No.2, 273-279, 2016

8th, 2018

Title:

The cytotoxicity of organobismuth compounds with certain molecular structures can be diminished by replacing the bismuth atom with an antimony atom in the molecules

Author:

Kumiko Kohri, Eiko Yoshida, Shuji Yasuike, Tomoya Fujie, Chika Yamamoto, Toshiyuki Kaji

J. Toxicol. Sci. Vol.40, No.3, 321-327, 2015

Title:

In silico risk assessment for skin sensitization using artificial neural network analysis

Author:

Kyoko Tsujita-Inoue, Tomomi Atobe, Morihiko Hirota, Takao Ashikaga, Hirokazu Kouzuki

J. Toxicol. Sci. Vol.40, No.2, 193-209, 2015

Title:

Chromium (VI)-induced transformation is enhanced by Zn deficiency in BALB/c 3T3 cells

Author:

Tomoki Kimura, Akira Onodera, Fumika Okumura, Tsuyoshi Nakanishi, Norio Itoh

J. Toxicol. Sci. Vol.40, No.3, 383-387, 2015

Title:

Hand1-Luc Embryonic Stem Cell Test (Hand1-Luc EST): A novel rapid and highly reproducible in vitro test for embryotoxicity by measuring cytotoxicity and differentiation toxicity using engineered mouse ES cells

Author:

Florian Le Coz, Noriyuki Suzuki, Hirohisa Nagahori, Takashi Omori, Koichi Saito

J. Toxicol. Sci. Vol.40, No.2, 251-261, 2015

7th, 2017

Title:

New recreational drug 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (alpha-PVP) activates central nervous system via dopaminergic neuron

Author:

Asuka Kaizaki, Sachiko Tanaka and Satoshi Numazawa

J. Toxicol. Sci. Vol.39, No.1, 1-6, 2014

Title:

Involvement of epithelial-mesenchymal transition in methotrexate-induced pulmonary fibrosis

Author:

Masayuki Ohbayashi, Satoshi Kubota, Aya Kawase, Noriko Kohyama, Yasuna Kobayashi and Toshinori Yamamoto

J. Toxicol. Sci. Vol.39, No.2, 319-330, 2014

Title:

Effect of talaporfin sodium-mediated photodynamic therapy on cell death modalities in human glioblastoma T98G cells

Author:

Yuichi Miki, Jiro Akimoto, Michika Hiranuma and Yasuyuki Fujiwara

J. Toxicol. Sci. Vol.39, No.6, 821-827, 2014

Title:

FBXO6 attenuates cadmium toxicity in HEK293 cells by inhibiting ER stress and JNK activation

Author:

Ke Du, Tsutomu Takahashi, Shusuke Kuge, Akira Naganuma and Gi-Wook Hwang

J. Toxicol. Sci. Vol.39, No.6, 861-866, 2014

Title:

Early indicators of delayed adverse effects in female reproductive organs in rats receiving neonatal exposure to 17alpha-ethynylestradiol

Author:

Miwa Takahashi, Kaoru Inoue, Tomomi Morikawa, Saori Matsuo, Seigo Hayashi, Kei Tamura, Gen Watanabe, Kazuyoshi Taya and Midori Yoshida

J. Toxicol. Sci. Vol.39, No.5, 775-784, 2014

6th, 2016

Title:

Molecular mechanisms underlying ochratoxin A-induced genotoxicity: global gene expression analysis suggests induction of DNA double-strand breaks and cell cycle progression

Author:

Daisuke Hibi, Aki Kijima, Ken Kuroda, Yuta Suzuki, Yuji Ishii, Meilan Jin, Masahiro Nakajima, Yoshiko Sugita-Konishi, Tokuma Yanai, Takehiko Nohmi, Akiyoshi Nishikawa, Takashi Umemura

J. Toxicol. Sci. Vol.38, No.1, 57-69, 2013

Title:

Postnatal exposure to low-dose bisphenol A influences various emotional conditions

Author:

Tetsuya Fujimoto, Kazuhiko Kubo, Yasuo Nishikawa, Shuji Aou

J. Toxicol. Sci. Vol.38, No.4, 539-546, 2013

Title:

Neutrophil gelatinase-associated lipocalin, a sensitive urinary biomarker of acute kidney injury in dogs receiving gentamicin

Author:

Kiyonori Kai, Takashi Yamaguchi, Yu Yoshimatsu, Junzo Kinoshita, Munehiro Teranishi, Wataru Takasaki

J. Toxicol. Sci. Vol.38, No.2, 269-277, 2013

Title:

Genotoxicity and reactive oxygen species production induced by magnetite nanoparticles in mammalian cells

Author:

Masanobu Kawanishi, Sayaka Ogo, Miho Ikemoto, Yukari Totsuka, Kousuke Ishino, Keiji Wakabayashi, Takashi Yagi

J. Toxicol. Sci. Vol.38, No.3, 503-511, 2013

5th, 2015

Title:

Hair-to-blood ratio and biological half-life of mercury: experimental study of methylmercury exposure through fish consumption in humans

Author:

Kozue Yaginuma-Sakurai, Katsuyuki Murata, Miyuki Iwai-Shimada, Kunihiko Nakai, Naoyuki Kurokawa, Nozomi Tatsuta and Hiroshi Satoh

J. Toxicol. Sci. Vol.37, No.1, 123-130, 2012

Title:

Effects of sustained stimulation with multi-wall carbon nanotubes on immune and inflammatory responses in mice

Author:

Atsumi Yamaguchi, Tomoko Fujitani, Ken-ichi Ohyama, Dai Nakae, Akihiko Hirose, Tetsuji Nishimura and Akio Ogata

J. Toxicol. Sci. Vol.37, No.1, 177-189, 2012

Title:

Methylglyoxal activates the human transient receptor potential ankyrin 1 channel

Author:

Susumu Ohkawara, Toshiko Tanaka-Kagawa, Yoko Furukawa and Hideto Jinno

J. Toxicol. Sci. Vol.37, No.4, 831-835, 2012

4th, 2014

Title:

Protein disulfide isomerase knockdown-induced cell death is cell-line-dependent and involves apoptosis in MCF-7 cells

Author:

Tomoyo Hashida, Yaichiro Kotake, Shigeru Ohta

J. Toxicol. Sci. Vol.36, No.1, 1-7, 2011

Title:

Cadmium toxicity is caused by accumulation of p53 through the down-regulation of Ube2d family genes in vitro and in vivo

Author:

Maki Tokumoto, Yasuyuki Fujiwara, Akinori Shimada, Tatsuya Hasegawa, Yoshiyuki Seko, Hisamitsu Nagase, Masahiko Satoh

J. Toxicol. Sci. Vol.36, No.2, 191-200, 2011

Title:

Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury

Author:

Gi-Wook Hwang, Jin-Yong Lee, Katsunori Ryoke, Fujio Matsuyama, Jong-Mu Kim, Tsutomu Takahashi, Akira Naganuma

J. Toxicol. Sci. Vol.36, No.3, 389-391, 2011

3rd, 2013

Title:

Study on penetration of titanium dioxide (TiO2) nanoparticles into intact and damaged skin in vitro

Author:

Mika Senzui, Toshiaki Tamura, Keiko Miura, Yoshiaki Ikarashi,Yoshiteru Watanabe and Makiko Fujii

J. Toxicol. Sci., Vol. 35, No. 1, 107-113, 2010

Title:

Prenatal exposure to titanium dioxide nanoparticles increases dopamine levels in the prefrontal cortex and neostriatum of mice

Author:

Yuta Takahashi, Keisuke Mizuo, Yusuke Shinkai, Shigeru Oshio and Ken Takeda

J. Toxicol. Sci., Vol. 35, No. 5, 749-756, 2010

Title:

Immunochemical method to detect proteins that undergo selective modification by 1,2-naphthoquinone derived from naphthalene through metabolic activation

Author:

Takashi Miura and Yoshito Kumagai

J. Toxicol. Sci., Vol. 35, No. 6, 843-852, 2010

2nd, 2012

Title:

Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats

Author:

Yoshimitsu Sakamoto, Dai Nakae, Kuniaki Tayama, Akihiko Maekawa, Kiyoshi Imai, Akihiko Hirose, Tetsuji Nishimura and Akio Ogata

J. Toxicol. Sci., Vol. 34, No. 1, PP.65-76 (2009)

Title:

Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist

Author:

Katsunori Yamaura, Eriko Suwa, Hiromi Sato and Koichi Ueno

J. Toxicol. Sci., Vol. 34, No. 4, PP.427-431 (2009)

Title:

Acute toxicity of pharmaceutical and personal care products on freshwater crustacean (Thamnocephalus platyurus) and fish (Oryzias latipes)

Author:

Joon-Woo Kim, Hiroshi Ishibashi, Yuji Takao, Masashi Hirano, Minoru Koga and Koji Arizono

J. Toxicol. Sci., Vol. 34, No. 2, PP.227-232 (2009)

1st, 2011

Title:

Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube

Author:

Atsuya Takagi, Akihiko Hirose, Tetsuji Nishimura, Nobutaka Fukumori, Akio Ogata, Norio Ohashi, Satoshi Kitajima and Jun Kanno

J. Toxicol. Sci., Vol. 33, No. 1, PP.105-116, 2008

Title:

Production of IL-8 in THP-1 cells following contact allergen stimulation via mitogen-activated protein kinase activation or tumor necrosis factor-α production

Author:

Yuko Nukada, Masaaki Miyazawa, Nanae Kosaka, Yuichi Ito, Hitoshi Sakaguchi and Naohiro Nishiyama

J. Toxicol. Sci., Vol. 33, No. 2, PP.175-185, 2008

Title:

Role of MAPK signaling pathway in the activation of dendritic type cell line, THP-1, induced by DNCB and NiSO4

Author:

Masaaki Miyazawa, Yuichi Ito, Nanae Kosaka, Yuko Nukada, Hitoshi Sakaguchi, Hiroyuki Suzuki and Naohiro Nishiyama

J. Toxicol. Sci., Vol. 33, No. 1, PP.51-59, 2008

Title:

Strain differences in hepatic cytochrome P450 1A and 3A expression between Sprague-Dawley and Wistar rats

Author:

Tomoyuki Kishida, Shin-ichi Muto, Morimichi Hayashi, Masaru Tsutsui, Satoru Tanaka, Makoto Murakami and Junji Kuroda

J. Toxicol. Sci., Vol. 33, No. 4, PP.447-457, 2008

Title:

Comparative study of histamine H4 receptor expression in human dermal fibroblasts

Author:

Yoshiko Ikawa, Kayoko Shiba, Emi Ohki, Nanami Mutoh, Masahiko Suzuki, Hiromi Sato and Koichi Ueno

J. Toxicol. Sci., Vol. 33, No. 4, PP.503-508, 2008