The Journal of Toxicological Sciences

Archive

Vol.46, No.12, 553-618, 2021

Pharmacokinetics of primary metabolites 5-hydroxythalidomide and 5′-hydroxythalidomide formed after oral administration of thalidomide in the rabbit, a thalidomide-sensitive species
Makiko Kuwagata, Takuro Hasegawa, Hiromasa Takashima, Makiko Shimizu, Satoshi Kitajima, Hiroshi Yamazaki
J. Toxicol. Sci., Vol.46, No.12, 553-560, 2021
Corneal lesions related to an anesthetic mixture of medetomidine, midazolam, and butorphanol treatment in rats
Kyohei Kamio, Junya Morita, Yutaka Nakanishi, Minoru Sasaki, Masaki Wakamatsu
J. Toxicol. Sci., Vol.46, No.12, 561-568, 2021
Association between in vitro nuclear receptor-activating profiles of chemical compounds and their in vivo hepatotoxicity in rats
Susumu Kodama, Nao Yoshii, Akihiro Ota, Jun-ichi Takeshita, Kouichi Yoshinari, Atsushi Ono
J. Toxicol. Sci., Vol.46, No.12, 569-587, 2021
Effects of excessive sodium chloride loading in the spontaneously diabetic torii (SDT) fatty rats, a preclinical model of type 2 diabetes mellitus
Soon Hui Teoh, Katsuhiro Miyajima, Yuichi Shinozaki, Masami Shinohara, Keiichi Ohata, François Briand, Rika Morimoto, Yuka Nakamura, Kinuko Uno, Noriko Kemuriyama, Dai Nakae, Takeshi Ohta, Tatsuya Maekawa
J. Toxicol. Sci., Vol.46, No.12, 589-599, 2021
Elucidation of the species differences of epyrifenacil-induced hepatotoxicity between mice and humans by mass spectrometry imaging analysis in chimeric mice with humanized liver
Kohei Matsunaga, Jun Abe, Keiko Ogata, Satoki Fukunaga, Sachiko Kitamoto
J. Toxicol. Sci., Vol.46, No.12, 601-609, 2021
Detection of double-stranded DNA breaks and apoptosis induced by bleomycin in mouse intestine
Togo Ikuta, Aki Koike, Manabu Koike
J. Toxicol. Sci., Vol.46, No.12, 611-618, 2021

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