The Journal of Toxicological Sciences

Vol.50, No.12, 2025

Coptisine improves sepsis-induced acute kidney injury by inhibiting ferroptosis

Yu Zhang, Junjun Huang, Xiaoyan Ji and Ke Ren

J. Toxicol. Sci., Vol.50, No.12, 649-659, 2025

Effects of food restriction and sex hormonal intervention on alkaline phosphatase isoenzymes in serum, liver, bone and small intestine of rats

Aya Hasegawa-Izaki, Junya Morita, Yuka Kirihata, Natsuki Tanaka, Chihiro Noguchi, Kenta Matsue, Yasuhiro Kurihara, Satoshi Tsuji, Aiko Ishii and Masaki Wakamatsu

J. Toxicol. Sci., Vol.50, No.12, 661-675, 2025

Lenvatinib induces diarrhea in rats by promoting intestinal barrier injury via targeting AQP4

Guanbao Long, Xin Li, Chaowen Xiao, Lu Tan and Changchun Cai

J. Toxicol. Sci., Vol.50, No.12, 677-690, 2025

Rodent-specific induction of cholestasis and cholangioma through the reduction of bile salt export pump by bardoxolone methyl

Hironori Otsuki, Tetsuro Araki, Atsuko Takami, Koji Inomata, Masanori Hiura, Ken-ichiro Nan-ya and Kouichi Yoshinari

J. Toxicol. Sci., Vol.50, No.12, 691-705, 2025

Quantitative analysis of Cyp1a2 expression and temporal characterization of zonation structure formation during mouse liver development

Mako Ichikawa, Miyuki Yagi, Kurumi Miyazawa, Hiromasa Muto, Hiromasa Kato and Wataru Ochiai

J. Toxicol. Sci., Vol.50, No.12, 707-715, 2025

Protective effects of retinoic acid on cadmium toxicity in human proximal tubular epithelial cells

Jin-Yong Lee, Chikage Mori, Maki Tokumoto and Masahiko Satoh

J. Toxicol. Sci., Vol.50, No.12, 717-725, 2025

Renal effects of excessive fructose intake in Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats

Kaoru Toyoda, Tadakazu Takahashi, Yuki Tanaka, Yusuke Suzuki, Hideaki Yokoyama, Toshiyuki Shoda, James K. Chambers and Kazuyuki Uchida

J. Toxicol. Sci., Vol.50, No.12, 727-740, 2025

News & Announcement

1-May-2025: Vol.50, No.5 was released on the Web.
21-April-2025: From June 1, 2025, this journal will update its copyright policy and introduce an open Creative Commons license. Please note that the “Instructions for Authors” will be completely revised in line with this.
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2-July-2021: Impact factor 2020: The latest impact factor is 2.196.
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Copyright Permission page has been updated.
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2-August-2019: Vol.44, No.8 was released on the Web.
12-July-2019: Impact Factor 2018: The latest impact factor is 1.732.
2-July-2019: Vol.44, No.7 was released on the Web.
4-June-2019: Vol.44, No.6 was released on the Web.
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3-August-2018: Vol.43, No.8 was released on the Web.
6-July-2018: Vol.43, No.7 was released on the Web.
27-June-2018: Impact Factor 2017: The latest impact factor is 1.719.
27-June-2018: Archive page is newly opened.
1-June-2018: Renewed HP of The Journal of Toxicological Sciences.
Notice: Instructions for Authors and Article Processing Charge are revised.

SciEd ver.1 is shown for reference only.
This journal is supported by
JSPS KAKENHI Grant Number JP19HP2004.

Title: The Journal of Toxicological Sciences

Abbreviation: J. Toxicol. Sci.

Publisher: The Japanese Society of Toxicology

Editor-in-Chief: Toshiyuki Kaji

Frequency of Publication: monthly

Editorial Office:
Faculty of Pharmaceutical Sciences
Tokyo University of Science
2641 Yamazaki, Noda 278-8510 JAPAN

E-mail: jts-ed@jtoxsci.org

ISSN	Online ISSN: 1880-3989
	Print ISSN: 0388-1350